The Simpsons

The Simpsons is a diabolically funny television show created by Matt Groening. It's a cartoon about an all-American family, whose father is fat and lazy, mother is a gifted housewife, son is a evil demon, daughter is an unnoticed genius, and baby is... well, a baby.

The Simpsons first aired on the FOX network on January 14th, 1990 and has become the longest running animated TV show ever.

Links - The Simpson's official page.
IMDB Page.